Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | CTSG | P08311 | 2/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.37 |
| ▸ | CMA1 | P23946 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518220 | 1.00 | AKT1 (0.41) | AKT1CTSKCTSSPRSS1CTSG | |
| SCHEMBL7661604 | 0.92 | AKT1 (0.40) | AKT1CTSKCTSSPRSS1CTSG | |
| SCHEMBL7661602 | 0.92 | AKT1 (0.40) | AKT1CTSKCTSSPRSS1CTSG | |
| SCHEMBL8397586 | 0.88 | AKT1 (0.43) | AKT1CTSKCTSSGSTO1 | |
| SCHEMBL7656204 | 0.84 | PPARA (0.46) | AKT1CTSSL3MBTL1 | |
| SCHEMBL7601470 | 0.82 | AKT1 (0.42) | AKT1CTSKCTSS | |
| SCHEMBL8579974 | 0.82 | CTSK (0.40) | AKT1CTSKCTSSTSHR | |
| SCHEMBL6432521 | 0.79 | PPARA (0.43) | AKT1CTSSL3MBTL1 | |
| SCHEMBL8556956 | 0.78 | CYP1A2 (0.36) | AKT1CTSKCTSS | |
| SCHEMBL8088177 | 0.77 | ATM (0.39) | CTSKCTSSTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915829-A1 | DIAGNOSTIC IMAGING CONTRAST AGENT WITH IMPROVED IN-SERUM-RELAXIVITY | BRACCO S.p.A. (IT) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998005625-A1 | DIAGNOSTIC IMAGING CONTRAST AGENT WITH IMPROVED IN-SERUM-RELAXIVITY | BRACCO S.P.A. (IT) | 1998-02-12 | — | — | WO | disclosed |