Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397586 | 0.92 | AKT1 (0.43) | AKT1ITGA4ITGB7ATMCTSS | |
| SCHEMBL7666444 | 0.91 | ATM (0.40) | AKT1ITGA4ITGB7MAPTTDP1 | |
| SCHEMBL7595591 | 0.89 | ITGA4 (0.41) | ITGA4ITGB7MAPTTDP1ATM | |
| SCHEMBL7661604 | 0.88 | AKT1 (0.40) | AKT1ITGA4ITGB7CTSSCTSK | |
| SCHEMBL7661602 | 0.88 | AKT1 (0.40) | AKT1ITGA4ITGB7CTSSCTSK | |
| SCHEMBL8874523 | 0.86 | ITGA4 (0.40) | AKT1ITGA4ITGB7MAPTTDP1 | |
| SCHEMBL6432521 | 0.86 | PPARA (0.43) | AKT1CTSSKLK5 | |
| SCHEMBL7597532 | 0.84 | ITGA4 (0.52) | ITGA4ITGB7MAPTTDP1ATM | |
| SCHEMBL7597534 | 0.84 | ITGA4 (0.52) | ITGA4ITGB7MAPTTDP1ATM | |
| SCHEMBL8518225 | 0.82 | AKT1 (0.41) | AKT1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061956-B1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO SPA (IT) | 2002-12-11 | — | — | EP | disclosed |
| US-6403055-B1 | CARBOXYLATED POLYAMINE COMPOUND | DIBRA S.P.A. (IT) | 2002-06-11 | — | — | US | disclosed |
| US-6337064-B1 | USED AS CONTRAST AGENT IN MAGNETIC RESONANCE IMAGING, MEDICAL DIAGNOSIS | DIBRA S.P.A. (IT) | 2002-01-08 | — | — | US | disclosed |
| EP-1061956-A1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO S.p.A. (IT) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999045967-A1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO S.P.A. (IT) | 1999-09-16 | — | — | WO | disclosed |