Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518318 | 1.00 | GPR84 (0.36) | GPR84PRCPKIF11MAOBFFAR4 | |
| SCHEMBL8518012 | 0.88 | CYP17A1 (0.39) | GPR84KIF11MAOBTAAR1HRH3 | |
| SCHEMBL8518015 | 0.88 | CYP17A1 (0.39) | GPR84KIF11MAOBTAAR1HRH3 | |
| SCHEMBL8041175 | 0.88 | CYP17A1 (0.39) | GPR84KIF11MAOBTAAR1HRH3 | |
| SCHEMBL9255736 | 0.86 | PROKR1 (0.34) | MAOBTAAR1KCNH2HTR2A | |
| SCHEMBL9255744 | 0.86 | PROKR1 (0.34) | MAOBTAAR1KCNH2HTR2A | |
| SCHEMBL9255752 | 0.86 | PROKR1 (0.34) | MAOBTAAR1KCNH2HTR2A | |
| SCHEMBL8518370 | 0.85 | GPR84 (0.34) | GPR84PRCPMAOBFFAR4MCHR1 | |
| SCHEMBL8518373 | 0.85 | GPR84 (0.34) | GPR84PRCPMAOBFFAR4MCHR1 | |
| SCHEMBL8518372 | 0.85 | GPR84 (0.34) | GPR84PRCPMAOBFFAR4MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475273-B1 | Liquid crystal mixture containing halogenated alcenyl compounds | MERCK PATENT GMBH (DE) | 1999-04-07 | — | — | EP | disclosed |
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0475273-A1 | Halogenated alcenyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |