Styrene

Styrene

SCHEMBL8518322

C=Cc1ccccc1.CCCCOC(=O)OC(C)=O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.45
TDP1 Q9NUW8 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
ALDH1A1 P00352 5/20 0.42
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 2/20 0.42
HPGD P15428 2/20 0.41
KDM4E B2RXH2 1/20 0.41
TP53 P04637 1/20 0.41
HSD17B10 Q99714 1/20 0.40
LMNA P02545 2/20 0.40
RECQL P46063 1/20 0.39
ELANE P08246 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL2734707 0.88 ALDH1A1 (0.56) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
Styrene SCHEMBL27928969 0.82 TSHR (0.50) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
Styrene SCHEMBL10384254 0.82 ALDH1A1 (0.49) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
Styrene SCHEMBL6556236 0.82 TSHR (0.55) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
Styrene SCHEMBL141229 0.82 TSHR (0.55) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
Styrene SCHEMBL4798421 0.82 TSHR (0.63) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
Styrene SCHEMBL67823 0.81 TSHR (0.67) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
Styrene SCHEMBL10459189 0.81 ATM (0.61) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
Styrene SCHEMBL11162678 0.81 ATM (0.61) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
Styrene SCHEMBL28887747 0.81 TSHR (0.67) TSHRTDP1L3MBTL1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5868261-A Anti-slamming latch apparatus for modular component installations DIGITAL EQUIPMENT CORPORATION (US) 1999-02-09 US disclosed
EP-0843510-A2 Anti-slamming latching apparatus for modular component installations DIGITAL EQUIPMENT CORPORATION (US) 1998-05-20 EP disclosed