⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15344088 | 0.83 | ALDH1A1 (0.48) | — | |
| SCHEMBL2932685 | 0.82 | — | — | |
| SCHEMBL2254856 | 0.79 | — | — | |
| SCHEMBL17415916 | 0.78 | PAOX (0.52) | — | |
| SCHEMBL11809606 | 0.78 | PAOX (0.52) | — | |
| SCHEMBL15328412 | 0.78 | ALDH1A1 (0.43) | — | |
| SCHEMBL10462001 | 0.78 | ALDH1A1 (0.60) | — | |
| SCHEMBL3360813 | 0.75 | — | — | |
| SCHEMBL16024409 | 0.75 | CA1 (0.42) | — | |
| SCHEMBL21127531 | 0.75 | CA1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11269149-A | — | — | None | — | — | JP | disclosed |
| US-20230322815-A1 | NOVEL COMPOUNDS AND THERAPEUTIC USES THEREOF | UNIVERSITY OF HUDDERSFIELD (GB) | 2023-10-12 | — | — | US | disclosed |
| CN-109134704-A | A kind of application of chitosan oligosaccharide thiourea derivatives, nano silver prepared therefrom and the nano silver | 河南农业大学 | 2019-01-04 | — | — | CN | disclosed |
| CN-1284073-A | 5- (2-imidazolinylamino) -benzimidazole derivatives, their preparation and their use as alpha-adrenergic receptor agonists with improved metabolic stability | PROCTER & GAMBLE (US) | 2001-02-14 | — | — | CN | disclosed |
| JP-H11269149-A | PRODUCTION OF 2-IMINOIMIDAZOLIDINES | SHIRATORI SEIYAKU KK | 1999-10-05 | — | — | JP | disclosed |
| EP-0549755-A4 | — | — | 1994-03-30 | — | — | EP | disclosed |
| EP-0549755-A1 | ddI IMMUNOASSAYS, DERIVATIVES, CONJUGATES AND ANTIBODIES | SIGMA CHEMICAL COMPANY (US) | 1993-07-07 | — | — | EP | disclosed |
| WO-1992022639-A1 | ddI IMMUNOASSAYS, DERIVATIVES, CONJUGATES AND ANTIBODIES | SIGMA CHEMICAL COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |