Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518970 | 0.91 | PTGS2 (0.46) | ABCB11PTGS2STSALDH1A1LMNA | |
| SCHEMBL8520249 | 0.90 | PTGS2 (0.46) | ABCB11PTGS2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8518908 | 0.88 | ABCB11 (0.57) | ABCB11PTGS2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8519020 | 0.88 | PTGS2 (0.44) | ABCB11PTGS2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8518955 | 0.87 | ABCB11 (0.43) | ABCB11PTGS2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8519387 | 0.87 | ABCB11 (0.41) | ABCB11PTGS2STSALDH1A1LMNA | |
| SCHEMBL8519390 | 0.85 | ABCB11 (0.42) | ABCB11PTGS2STSALDH1A1LMNA | |
| SCHEMBL8519097 | 0.82 | ABCB11 (0.40) | ABCB11PTGS2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8519153 | 0.81 | STS (0.43) | ABCB11PTGS2STSALDH1A1LMNA | |
| SCHEMBL8520084 | 0.79 | ABCB11 (0.33) | ABCB11PTGS2ALDH1A1LMNACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952368-A | AN INHIBITORS OF PROSTAGLANDIN G/H SYNTHASE, ANTIINFLAMMATORY AND ANALGESIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1999-09-14 | — | — | US | disclosed |