Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 6/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10891430 | 0.91 | CYP2C9 (0.46) | CYP2C9CYP2C19SMN1; SMN2HIF1ATP53 | |
| SCHEMBL27861556 | 0.89 | ALOX15 (0.43) | CYP2C9CYP2C19SMN1; SMN2HIF1ATP53 | |
| SCHEMBL27877808 | 0.81 | ALDH1A1 (0.46) | CYP2C9CYP2C19SMN1; SMN2HIF1ATP53 | |
| SCHEMBL68860 | 0.79 | CYP2C9 (0.48) | CYP2C9CYP2C19SMN1; SMN2HIF1ATP53 | |
| SCHEMBL27745048 | 0.77 | HTT (0.43) | CYP2C9CYP2C19SMN1; SMN2HIF1ATP53 | |
| SCHEMBL131955 | 0.76 | CYP2C9 (0.50) | CYP2C9CYP2C19SMN1; SMN2HIF1ATP53 | |
| SCHEMBL12620456 | 0.76 | CYP2C19 (0.47) | CYP2C9CYP2C19SMN1; SMN2HIF1ATP53 | |
| SCHEMBL12671647 | 0.74 | CYP3A4 (0.48) | CYP2C9CYP2C19SMN1; SMN2HIF1AALOX15 | |
| SCHEMBL30640814 | 0.74 | HTT (0.47) | CYP2C9CYP2C19SMN1; SMN2HIF1ATP53 | |
| SCHEMBL27286157 | 0.74 | ALOX15 (0.43) | CYP2C9CYP2C19SMN1; SMN2HIF1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36128-E | STABILIZER FOR ORGANIC COMPOUNDS | ALBEMARLE CORPORATION (US) | 1999-03-02 | — | — | US | disclosed |
| EP-0280938-B1 | Antioxidant aromatic fluorophosphites | ETHYL CORP (US) | 1994-06-15 | — | — | EP | disclosed |
| US-4912155-A | Containing substituted aryl group | ETHYL CORPORATION (US) | 1990-03-27 | — | — | US | disclosed |
| EP-0280938-A1 | Antioxidant aromatic fluorophosphites | ALBEMARLE CORPORATION (US) | 1988-09-07 | — | — | EP | disclosed |