SCHEMBL336495

SCHEMBL336495

CN(CC(=O)O)C(=O)OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 2/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
MVD P53602 1/20 0.36
CTSL P07711 2/20 0.34
CTSB P07858 2/20 0.34
CTSS P25774 2/20 0.34
SLC6A4 P31645 2/20 0.34
CTSD P07339 1/20 0.34
HTR2C P28335 1/20 0.34
CA14 Q9ULX7 1/20 0.33
CACNA1G O43497 1/20 0.33
CACNA1B Q00975 1/20 0.33
CACNA1C Q13936 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
EYA2 O00167 1/20 0.32
APP P05067 1/20 0.32
ACE P12821 1/20 0.32
GBA1 P04062 1/20 0.32
DGAT1 O75907 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29062672 0.98 HDAC6 (0.36) HDAC6HDAC1HDAC2MVDCTSL
SCHEMBL397071 0.92 MVD (0.39) HDAC6HDAC1HDAC2MVDCTSL
SCHEMBL21069315 0.92 MVD (0.39) HDAC6HDAC1HDAC2MVDCTSL
SCHEMBL25134161 0.92 MVD (0.39) HDAC6HDAC1HDAC2MVDCTSL
SCHEMBL25133621 0.92 MVD (0.39) HDAC6HDAC1HDAC2MVDCTSL
SCHEMBL17873895 0.86 HDAC6 (0.34) HDAC6HDAC1HDAC2MVDCA14
Hydrochloric Acid SCHEMBL22492432 0.84 HDAC6 (0.33) HDAC6HDAC1HDAC2CA14
SCHEMBL1455952 0.83 MVD (0.38) HDAC6HDAC1HDAC2MVDCA14
SCHEMBL6445026 0.83 HDAC6 (0.37) HDAC6HDAC1HDAC2CTSLCTSB
SCHEMBL256557 0.83 HDAC6 (0.37) HDAC6HDAC1HDAC2CTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1974 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024189550-A1 PROCESS FOR THE PREPARATION OF ISAVUCONAZONIUM SULFATE AND ITS CRYSTALLINE FORMS APITORIA PHARMA PRIVATE LIMITED (IN) 2024-09-19 WO claimed
CN-118085005-A 18 Beta-glycyrrhetinic acid derivative and preparation method and application thereof 石河子大学 2024-05-28 CN claimed
US-20240010644-A1 PROCESS FOR THE PREPARATION OF ISAVUCONAZONIUM SULFATE CITIBANK, N.A. 2024-01-11 US claimed
CN-107207562-A Prodrugs of 17 beta-HSD 1 inhibitors 佛恩多制药有限公司 2017-09-26 CN claimed
EP-2699557-B1 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS BIOTA SCIENT MANAGEMENT (AU) 2017-08-16 EP claimed
EP-2621919-B1 PHENYLQUINAZOLINE DERIVATIVES MERCK PATENT GMBH (DE) 2016-01-13 EP claimed
EP-2199275-B1 INHIBITOR OF ISCHEMIC DISORDERS UNIV FUKUOKA (JP) 2016-01-13 EP claimed
US-7776855-B2 Antimicrobial oxazolidinone prodrugs JANSSEN PHARMACEUTICA N.V. (BG) 2010-08-17 US claimed
US-20080027053-A1 ANTIMICROBIAL OXAZOLIDINONE PRODRUGS JANSSEN PHARMACEUTICA N.V. (BE) 2008-01-31 US claimed
WO-2008014108-A2 ANTIMICROBIAL OXAZOLIDINONE PRODRUGS JANSSEN PHARMACEUTICA N.V. (BE) 2008-01-31 WO claimed
EP-0549727-A1 CARBOXYLIC ACID ESTERS OF RAPAMYCIN AMERICAN HOME PRODUCTS CORPORATION (US) 1993-07-07 EP claimed
US-5130307-A Antibody inhibitors; treating organ graft rejection, fungal infections; antiinflammatory agents AMERICAN HOME PRODUCTS CORPORATION (US) 1992-07-14 US claimed
WO-1992005179-A1 CARBOXYLIC ACID ESTERS OF RAPAMYCIN AMERICAN HOME PRODUCTS CORPORATION (US) 1992-04-02 WO claimed
WO-2026107097-A1 SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF ENLAZA THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
US-20260132139-A1 HIV INHIBITOR COMPOUNDS GILEAD SCIENCES INC (US) 2026-05-14 US disclosed
EP-4739672-A1 NEW COMPOUNDS Aston University (GB) 2026-05-13 EP disclosed
US-4432971-A HYPOTENSIVE AGENTS AND ANGIOTENSIN INHIBITION E. R. SQUIBB & SONS, INC. (US) 1984-02-21 US disclosed
EP-0071544-A1 Phosphonamidate compounds E.R. Squibb & Sons, Inc. (US) 1983-02-09 EP disclosed
US-4204991-A Sarcosine1 dehydroalanine8 angiotensin II derivatives G. D. SEARLE & CO. (US) 1980-05-27 US disclosed
US-3988467-A Aminoacyl compounds CIBA-GEIGY CORPORATION (US) 1976-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027053-A1 ANTIMICROBIAL OXAZOLIDINONE PRODRUGS OXA1L, PGLS, CYP51A1 HDAC6 542/4885HDAC1 82/4885HDAC2 313/4885
US-20240010644-A1 PROCESS FOR THE PREPARATION OF ISAVUCONAZONIUM SULFATE STS, MPST, SULT1A1 HDAC6 452/4885HDAC1 1176/4885HDAC2 1720/4885
US-20260132139-A1 HIV INHIBITOR COMPOUNDS SLC11A2, SLC6A15, NHERF1 HDAC6 2384/4885HDAC1 689/4885HDAC2 1023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.