Crotonaldehyde

Crotonaldehyde

SCHEMBL8519220

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nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

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Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 1.00
MAPK1 P28482 1/20 1.00
ALDH1A1 P00352 2/20 0.71
TSHR P16473 1/20 0.42
GAPDH P04406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Crotonaldehyde SCHEMBL254155 1.00 TRPA1 (1.00) TRPA1MAPK1ALDH1A1TSHRGAPDH
Crotonaldehyde SCHEMBL38450 1.00
Crotonaldehyde SCHEMBL3482634 1.00
Crotonaldehyde SCHEMBL38449 1.00
Crotonaldehyde SCHEMBL11158005 0.96
Crotonaldehyde SCHEMBL3111545 0.96
Crotonaldehyde SCHEMBL3118858 0.96
Crotonaldehyde SCHEMBL11330065 0.96
Crotonaldehyde SCHEMBL676405 0.96
Crotonaldehyde SCHEMBL38651242 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108072706-A Method for measuring content of acrolein in liquid phase mixture 中国石油天然气股份有限公司 2018-05-25 CN disclosed
CN-106248845-B Method for measuring content of unsaturated aldehyde in liquid phase mixture 中国石油天然气股份有限公司 2018-05-04 CN disclosed
US-5886234-A USING A SOLID ACID CATALYST TO REACT AN UNSATUREATIED ALDEHYDE E.G. CROTONALDEHYDE, AND A CYCLIC CONJUGATED DIENE, E.G CYCLOPENTADIENE, CYCLOHEXA-1,3-DIENE, IN AN EFFICIENT DIELS-ALDER REACTION IDEMITSU KOSAN CO., LTD. (JP) 1999-03-23 US disclosed