Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11357473 | 0.82 | KMT2A (0.56) | KMT2AENPP2KDM4EALDH1A1GAA | |
| SCHEMBL14039272 | 0.79 | KMT2A (0.57) | KMT2AENPP2KDM4EALDH1A1GAA | |
| SCHEMBL2820859 | 0.79 | KMT2A (0.53) | KMT2AENPP2KDM4EALDH1A1GAA | |
| SCHEMBL30402668 | 0.79 | KDM4E (0.51) | ENPP2KDM4EALDH1A1GAAGLA | |
| SCHEMBL23742484 | 0.79 | FLT3 (0.44) | KDM4EALDH1A1NPC1 | |
| SCHEMBL7965109 | 0.78 | KMT2A (0.54) | KMT2AKDM4EALDH1A1GAAGLA | |
| SCHEMBL6501337 | 0.77 | ENPP2 (0.64) | KMT2AENPP2KDM4EALDH1A1GAA | |
| SCHEMBL3155115 | 0.76 | KDM4E (0.47) | ENPP2KDM4EALDH1A1GAAGLA | |
| SCHEMBL3155202 | 0.76 | KDM4E (0.47) | KMT2AENPP2KDM4EALDH1A1GAA | |
| SCHEMBL23414621 | 0.76 | HSD17B10 (0.53) | ENPP2KDM4EALDH1A1GAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547708-B1 | Saccharin derivative proteolytic enzyme inhibitors | SANOFI SYNTHELABO (FR) | 2003-02-26 | — | — | EP | disclosed |