Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | ESR1 | P03372 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.67 |
| ▸ | ATM | Q13315 | 2/20 | 0.67 |
| ▸ | PGR | P06401 | 1/20 | 0.67 |
| ▸ | AR | P10275 | 1/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | STS | P08842 | 3/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.55 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11481676 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2ESR1LMNAADORA3ATM | |
| SCHEMBL9711179 | 0.89 | ESR1 (0.62) | SMN1; SMN2ESR1LMNAADORA3ATM | |
| SCHEMBL9558249 | 0.88 | LMNA (0.69) | SMN1; SMN2ESR1LMNAPGRSLC6A3 | |
| SCHEMBL14652461 | 0.88 | LMNA (0.69) | SMN1; SMN2ESR1LMNAPGRSLC6A3 | |
| SCHEMBL11209381 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2ESR1LMNAADORA3ATM | |
| SCHEMBL351005 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2ESR1LMNAADORA3ATM | |
| SCHEMBL351004 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2ESR1LMNAADORA3ATM | |
| SCHEMBL4969105 | 0.84 | HSD17B1 (0.71) | SMN1; SMN2ESR1LMNAPGRAR | |
| SCHEMBL5168726 | 0.84 | STS (0.71) | ESR1STSABCC4ABCC1CYP2C9 | |
| Estrone Acetate SCHEMBL20006536 | 0.83 | CYP3A4 (0.76) | SMN1; SMN2ESR1LMNAADORA3ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915905-A1 | PROCESS FOR PREPARING 16$g(a)-HYDROXY-ESTRA-1,3,5(10)-TRIENE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-05-19 | — | — | EP | disclosed |
| EP-0514187-B1 | Electrolytic cell and process for the labeling of proteins and peptides | DOW CHEMICAL CO (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1998004577-A1 | PROCESS FOR PREPARING 16α-HYDROXY-ESTRA-1,3,5(10)-TRIENE DERIVATIVES | SCHERING AG (DE) | 1998-02-05 | — | — | WO | disclosed |
| US-5246561-A | ELECTROLYTIC CELL AND PROCESS FOR THE LABELING OF PROTEINS AND PEPTIDES | THE DOW CHEMICAL COMPANY (US) | 1993-09-21 | — | — | US | disclosed |
| US-5230783-A | With radioactive materials | THE DOW CHEMICAL COMPANY (US) | 1993-07-27 | — | — | US | disclosed |
| WO-1992021019-A1 | ELECTROLYTIC CELL AND PROCESS FOR THE LABELING OF PROTEINS AND PEPTIDES | THE DOW CHEMICAL COMPANY (US) | 1992-11-26 | — | — | WO | disclosed |
| EP-0514187-A1 | Electrolytic cell and process for the labeling of proteins and peptides | THE DOW CHEMICAL COMPANY (US) | 1992-11-19 | — | — | EP | disclosed |