SCHEMBL8519478

SCHEMBL8519478

Cc1sccc1CCS(=O)(=O)O

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.33
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8520267 0.88 MGLL (0.34)
SCHEMBL9190475 0.72 NPSR1 (0.52) KDM4EALDH1A1HPGDHSD17B10
SCHEMBL4649171 0.71
SCHEMBL13992148 0.70 HTT (0.37) KDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL2307732 0.70
SCHEMBL16252214 0.69 PTPRC (0.30)
SCHEMBL3884582 0.69 TAAR1 (0.50) ALDH1A1HPGD
SCHEMBL31326844 0.69 TAAR1 (0.50) ALDH1A1HPGD
SCHEMBL10239998 0.69
SCHEMBL9243142 0.68 TYR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0262147-B1 SELF-DOPED POLYMERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-06-23 EP claimed
US-5891968-A Method of making self-doped zwitterionic heterocyclic polymers THE REGENTS OF UNIVERSITY OF CALIFORNIA (US) 1999-04-06 US disclosed
US-5589565-A Water-soluble conducting polyphenylene vinylene polymers THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-12-31 US disclosed
US-5569708-A POLYANILINES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-10-29 US disclosed