Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17281024 | 0.89 | HTT (0.39) | HTTGAAALDH1A1NPSR1TSHR | |
| SCHEMBL17790493 | 0.88 | HTT (0.38) | HTTGAAALDH1A1NPSR1TSHR | |
| SCHEMBL15440601 | 0.86 | LTB4R (0.37) | HTTGAAALDH1A1NPSR1TSHR | |
| SCHEMBL13937546 | 0.81 | HTT (0.39) | HTTGAAALDH1A1NPSR1TSHR | |
| SCHEMBL17790467 | 0.75 | LOX (0.40) | HTTGAAALDH1A1NPSR1TSHR | |
| SCHEMBL2040850 | 0.74 | ALDH1A1 (0.32) | HTTGAAALDH1A1 | |
| SCHEMBL16252173 | 0.73 | RELA (0.42) | HTTALDH1A1NPSR1TSHRRECQL | |
| SCHEMBL13145536 | 0.72 | NPSR1 (0.57) | NPSR1SMN1; SMN2 | |
| SCHEMBL12440735 | 0.71 | NOS3 (0.32) | HTTALDH1A1NPSR1 | |
| SCHEMBL8519478 | 0.70 | GSK3B (0.33) | ALDH1A1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150192555-A1 | Methods and Devices for Analytical Sensing of Biogenic Amines | UNIVERSITY OF SOUTH CAROLINA | 2015-07-09 | — | — | US | disclosed |
| US-8927293-B2 | Methods and devices for analytical sensing of biogenic amines | UNIVERSITY OF SOUTH CAROLINA (US) | 2015-01-06 | — | — | US | disclosed |
| US-20080299669-A1 | Methods and devices for analytical sensing of biogenic amines | SOUTH CAROLINA, UNIVERSITY OF | 2008-12-04 | — | — | US | disclosed |