SCHEMBL8519485

SCHEMBL8519485

[O]Cc1cc(C(F)(F)F)on1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.35
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14394656 0.79 L3MBTL1 (0.33) L3MBTL1MAPT
SCHEMBL412139 0.79 NOTUM (0.34) L3MBTL1
SCHEMBL3766102 0.79 L3MBTL1 (0.33) L3MBTL1
SCHEMBL17653862 0.77 AGBL2 (0.38) L3MBTL1CNR1CNR2MAPT
SCHEMBL5789048 0.76 SIRT2 (0.33) L3MBTL1
SCHEMBL9258998 0.75 L3MBTL1 (0.31) L3MBTL1
SCHEMBL18606355 0.75 L3MBTL1 (0.31) L3MBTL1
SCHEMBL15721247 0.75 L3MBTL1 (0.31) L3MBTL1
SCHEMBL12104852 0.71 PPARA (0.33) CNR1CNR2
SCHEMBL17653916 0.70 HDAC4 (0.40) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5935907-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1999-08-10 US disclosed