Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397549 | 0.85 | TSHR (0.38) | TSHRALOX12GLANPSR1HSD17B10 | |
| SCHEMBL8519229 | 0.84 | — | — | |
| SCHEMBL8400761 | 0.82 | GLA (0.44) | TSHRALOX12GLANPSR1HSD17B10 | |
| SCHEMBL8400772 | 0.81 | GLA (0.46) | TSHRALOX12GLANPSR1HSD17B10 | |
| SCHEMBL8401328 | 0.78 | GLRA3 (0.36) | TSHRALOX12GLANPSR1HSD17B10 | |
| SCHEMBL18982775 | 0.78 | CA2 (0.50) | TSHRALOX12NPSR1HSD17B10MEN1 | |
| SCHEMBL8397559 | 0.76 | RARB (0.42) | TSHRALOX12GLAHSD17B10MEN1 | |
| SCHEMBL7933969 | 0.76 | GLA (0.37) | TSHRALOX12GLANPSR1HSD17B10 | |
| SCHEMBL11813522 | 0.76 | GLA (0.55) | TSHRALOX12GLANPSR1HSD17B10 | |
| SCHEMBL7933971 | 0.73 | TSHR (0.36) | TSHRALOX12GLANPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |