Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.36 |
| ▸ | GLRB | P48167 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 3/20 | 0.35 |
| ▸ | RARG | P13631 | 3/20 | 0.35 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400789 | 0.84 | RARB (0.35) | TSHRRARBRARGRARAPTGDR | |
| SCHEMBL8397549 | 0.84 | TSHR (0.38) | GLATSHRALOX12RARBRARG | |
| SCHEMBL8399071 | 0.83 | GLA (0.40) | GLATSHRALOX12RARBRARG | |
| SCHEMBL7933969 | 0.82 | GLA (0.37) | GLRA3GLRBGLATSHRALOX12 | |
| SCHEMBL8400760 | 0.81 | TSHR (0.44) | GLATSHRALOX12RARBRARG | |
| SCHEMBL100584 | 0.79 | GLRA3 (0.50) | GLRA3GLRBCYP1A2CYP2D6MEN1 | |
| SCHEMBL6275312 | 0.79 | GLRA3 (0.50) | GLRA3GLRBCYP1A2CYP2D6MEN1 | |
| SCHEMBL7796578 | 0.79 | RARG (0.47) | GLRA3GLRBGLATSHRALOX12 | |
| SCHEMBL8519627 | 0.78 | TSHR (0.39) | GLATSHRALOX12CYP1A2CYP2D6 | |
| Methane SCHEMBL4556718 | 0.77 | GLRA3 (0.48) | GLRA3GLRBCYP1A2CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |