Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 11/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519666 | 1.00 | HCAR2 (0.52) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL8519665 | 0.90 | HCAR2 (0.43) | HCAR2TSHRMAPTCYP1A2KEAP1 | |
| SCHEMBL365676 | 0.90 | HCAR2 (0.43) | HCAR2TSHRMAPTCYP1A2KEAP1 | |
| SCHEMBL8948049 | 0.80 | HCAR2 (0.46) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL27601174 | 0.78 | HCAR2 (0.54) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL28308759 | 0.77 | KEAP1 (0.33) | HCAR2TSHRMAPTKEAP1NFE2L2 | |
| SCHEMBL25177775 | 0.73 | HCAR2 (0.48) | HCAR2TSHRTP53EGLN1EGLN3 | |
| Monomethyl Fumarate SCHEMBL1907622 | 0.72 | HCAR2 (0.94) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL28767804 | 0.72 | HCAR2 (0.41) | HCAR2ALDH1A1MAPTTDP1HSD17B10 | |
| Monomethyl Fumarate SCHEMBL1907625 | 0.72 | HCAR2 (0.94) | HCAR2TSHRTP53EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928820-A2 | Wet adhesion promoter | CYTEC TECHNOLOGY CORP. (US) | 1999-07-14 | — | — | EP | disclosed |