Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 10/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176808 | 0.89 | GNRHR (0.59) | GNRHR | |
| SCHEMBL8182738 | 0.78 | GNRHR (0.71) | GNRHR | |
| SCHEMBL8397440 | 0.77 | GNRHR (0.51) | GNRHR | |
| SCHEMBL8344835 | 0.77 | GNRHR (0.63) | GNRHR | |
| SCHEMBL7702565 | 0.69 | CYP2D6 (0.39) | GNRHR | |
| SCHEMBL8030149 | 0.67 | GNRHR (0.55) | GNRHR | |
| SCHEMBL7809400 | 0.67 | CYP11B1 (0.59) | — | |
| SCHEMBL6974460 | 0.66 | GNRHR (0.79) | GNRHR | |
| SCHEMBL8695292 | 0.66 | GNRHR (0.81) | GNRHR | |
| SCHEMBL8346371 | 0.66 | GNRHR (0.76) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981550-A | USEFUL IN TREATING A VARIETY OF SEX-HORMONE RELATED CONDITIONS IN BOTH MEN AND WOMEN, INCLUDING ENDOMETRIOSIS, UTERINE FIBROIDS, POLYCYSTIC OVARIAN DISEASE, HIRSUTISM, PRECOCIOUS PUBERTY, GONADAL STEROID-DEPENDENT NEOPLASIAS | MERCK & CO., INC. (US) | 1999-11-09 | — | — | US | disclosed |