Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.34 |
| ▸ | PTAFR | P25105 | 5/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | GNRHR | P30968 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176808 | 0.76 | GNRHR (0.59) | GNRHR | |
| SCHEMBL8519694 | 0.69 | GNRHR (0.55) | GNRHR | |
| SCHEMBL7696241 | 0.68 | GNRHR (0.47) | GNRHR | |
| SCHEMBL8397440 | 0.65 | GNRHR (0.51) | GNRHR | |
| SCHEMBL8344835 | 0.63 | GNRHR (0.63) | GNRHR | |
| SCHEMBL31061518 | 0.62 | CYP2A6 (1.00) | CYP2D6CYP2A6CYP2C9CYP2C19CYP2E1 | |
| SCHEMBL3615338 | 0.62 | CYP2A6 (1.00) | CYP2D6CYP2A6CYP2C9CYP2C19CYP2E1 | |
| SCHEMBL8182738 | 0.61 | GNRHR (0.71) | GNRHR | |
| SCHEMBL3609841 | 0.60 | CYP2A6 (0.71) | CYP2D6CYP2A6CYP2C9CYP2C19CYP2E1 | |
| SCHEMBL7698735 | 0.60 | GNRHR (0.60) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066477-A2 | IMIDAZOPYRIDINES | ASTRAZENECA AB (SE) | 2002-08-29 | — | — | WO | claimed |
| WO-2002066477-A2 | IMIDAZOPYRIDINES | ASTRAZENECA AB (SE) | 2002-08-29 | — | — | WO | disclosed |