SCHEMBL8519703

SCHEMBL8519703

N#CC=CCc1ccccc1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.46
ADRA2C P18825 1/20 0.40
KMT2A Q03164 1/20 0.40
PDCD1 Q15116 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
CYP2A6 P11509 1/20 0.36
HTR7 P34969 1/20 0.35
FOLH1 Q04609 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
KCNA5 P22460 1/20 0.34
KCNH2 Q12809 1/20 0.34
TACR1 P25103 3/20 0.33
HSD11B1 P28845 1/20 0.33
ALDH1A1 P00352 3/20 0.32
HSD17B10 Q99714 2/20 0.32
HPGD P15428 1/20 0.32
BCL2L1 Q07817 1/20 0.32
MAPK1 P28482 1/20 0.32
SLC6A2 P23975 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3804445 0.82 CYP1A1 (0.38) ALDH1A1HPGDPTGER4PTGER3PTGER2
SCHEMBL170431 0.76 DPP4 (0.55) DPP4ADRA2CKMT2APDCD1CD274
SCHEMBL8717020 0.76 DPP4 (0.50) DPP4KMT2APDCD1CD274CYP2A6
SCHEMBL28348557 0.76 DPP4 (0.55) DPP4ADRA2CKMT2APDCD1CD274
SCHEMBL27744825 0.75 GABRA1 (0.50) DPP4ADRA2CKMT2APDCD1CD274
SCHEMBL10599724 0.74 PTGER4 (0.50) DPP4KMT2APDCD1CD274CYP2A6
SCHEMBL10599731 0.74 PTGER4 (0.50) DPP4KMT2APDCD1CD274CYP2A6
SCHEMBL10390704 0.74 HSPA5 (0.45) HSD17B10CA12CA2CA9
Water SCHEMBL821345 0.73 DPP4 (0.52) DPP4KMT2APDCD1CD274CYP2A6
SCHEMBL5889006 0.73 DPP4 (0.47) DPP4KMT2APDCD1CD274CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0023447-B1 LIQUID CRYSTAL DISPLAY DEVICE AND SUBSCRIBER SET COMPRISING SUCH A DEVICE THOMSON-CSF (FR) 1983-04-06 EP claimed
JP-7286179-A None JP disclosed
EP-0927992-A1 MAGNETIC RECORDING MEDIUM AND MAGNETIC RECORDER/REPRODUCER COMPRISING THE SAME Sony Corporation (JP) 1999-07-07 EP disclosed
JP-H07286179-A SMECTIC LIQUID CRYSTAL COMPOSITION JAPAN ENERGY CORP 1995-10-31 JP disclosed
US-5138368-A Fabrication of printed wiring boards by projection imaging GREYHAWK SYSTEMS, INC. (US) 1992-08-11 US disclosed
WO-1990010047-A1 FABRICATION OF PRINTED WIRING BOARDS BY PROJECTION IMAGING GREYHAWK SYSTEMS, INC. (US) 1990-09-07 WO disclosed
EP-0023447-B1 LIQUID CRYSTAL DISPLAY DEVICE AND SUBSCRIBER SET COMPRISING SUCH A DEVICE THOMSON-CSF (FR) 1983-04-06 EP disclosed