SCHEMBL10599731

SCHEMBL10599731

C(=Cc1ccccc1)Cc1ccccc1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 2/20 0.50
PTGER3 P43115 2/20 0.50
PTGER2 P43116 2/20 0.50
DPP4 P27487 1/20 0.48
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
RECQL P46063 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
ALOX15 P16050 1/20 0.43
IDO1 P14902 2/20 0.41
PAM P19021 1/20 0.41
KCNA5 P22460 1/20 0.39
KCNH2 Q12809 1/20 0.39
HTR2A P28223 3/20 0.39
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10599724 1.00 PTGER4 (0.50) PTGER4PTGER3PTGER2DPP4KDM4E
(Z)-1,2-Diphenylethene SCHEMBL8333767 0.81 GABRA1 (0.46) DPP4ALDH1A1KMT2APDCD1CD274
SCHEMBL5011005 0.80 DPP4 (0.52) PTGER4PTGER3PTGER2DPP4ALDH1A1
SCHEMBL28348557 0.78 DPP4 (0.55) PTGER4PTGER3PTGER2DPP4ALDH1A1
SCHEMBL170431 0.78 DPP4 (0.55) PTGER4PTGER3PTGER2DPP4ALDH1A1
SCHEMBL8717020 0.78 DPP4 (0.50) PTGER4PTGER3PTGER2DPP4ALDH1A1
SCHEMBL2033548 0.76 PTGER4 (0.53) PTGER4PTGER3PTGER2KDM4EALDH1A1
SCHEMBL2033547 0.76 PTGER4 (0.53) PTGER4PTGER3PTGER2KDM4EALDH1A1
SCHEMBL28042952 0.76 DPP4 (0.47) PTGER4PTGER3PTGER2DPP4ALDH1A1
SCHEMBL5889006 0.76 DPP4 (0.47) DPP4ALDH1A1KMT2AKCNA5KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1215748-A Process for manufacturing solid composition with improved physical properties PROCTER & GAMBLE (US) 1999-05-05 CN disclosed
EP-0153729-B1 OPTICAL RECORDING MEDIUM TDK Corporation (JP) 1989-05-10 EP disclosed
US-4752820-A DIELECTRIC LIQUID CRYSTALS TDK CORPORATION (JP) 1988-06-21 US disclosed
EP-0153729-A1 Optical recording medium TDK Corporation (JP) 1985-09-04 EP disclosed