SCHEMBL8519722

SCHEMBL8519722

Cc1ccc2c(c1C)O[B]O2

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
TSHR P16473 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8519614 0.75 CYP1A2 (0.32) CYP1A2TSHR
SCHEMBL8518761 0.73 CYP2A6 (0.35) CYP1A2CYP2A6TSHRALDH1A1
SCHEMBL510833 0.70
SCHEMBL8519585 0.67
SCHEMBL13902883 0.64 ADRA2A (0.46) TSHRKDM4EALDH1A1HPGD
SCHEMBL8519720 0.64 KDM4E (0.34) KDM4EALDH1A1HPGD
SCHEMBL8519809 0.63
SCHEMBL15099397 0.62 AHR (0.47) CYP1A2CYP2A6TSHRKDM4EALDH1A1
SCHEMBL13138787 0.61 KDM4E (0.33) KDM4EALDH1A1HPGD
SCHEMBL12744378 0.61 ADORA2A (0.38) KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679662-B1 Catalyst component for the polymerization of olefins NIPPON OIL CO LTD (JP) 1999-07-14 EP disclosed
US-5728641-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1998-03-17 US disclosed
EP-0679662-A1 Catalyst component for the polymerization of olefins NIPPON OIL CO. LTD. (JP) 1995-11-02 EP disclosed