SCHEMBL8519720

SCHEMBL8519720

Cc1ccc2c(c1C)OBO2

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8519612 0.75 CYP1A2 (0.32)
SCHEMBL510833 0.70
SCHEMBL8519580 0.67
SCHEMBL12744378 0.65 ADORA2A (0.38) KDM4EALDH1A1HPGD
SCHEMBL13138787 0.65 KDM4E (0.33) KDM4EALDH1A1HPGD
SCHEMBL13902883 0.64 ADRA2A (0.46) KDM4EALDH1A1HPGD
SCHEMBL8519722 0.64 CYP1A2 (0.32) KDM4EALDH1A1HPGD
SCHEMBL15099397 0.62 AHR (0.47) KDM4EALDH1A1HPGD
SCHEMBL18194247 0.61 KDM4E (0.33) KDM4EALDH1A1HPGD
SCHEMBL5494672 0.61 TSHR (0.45) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679662-B1 Catalyst component for the polymerization of olefins NIPPON OIL CO LTD (JP) 1999-07-14 EP disclosed
US-5728641-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1998-03-17 US disclosed
EP-0679662-A1 Catalyst component for the polymerization of olefins NIPPON OIL CO. LTD. (JP) 1995-11-02 EP disclosed