Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.37 |
| ▸ | BID | P55957 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.37 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271436 | 1.00 | LIPG (0.46) | LIPGNR1H2NR1H3GPR3PTPN1 | |
| SCHEMBL12815176 | 1.00 | LIPG (0.46) | LIPGNR1H2NR1H3GPR3PTPN1 | |
| SCHEMBL6687946 | 0.94 | NR1H2 (0.38) | LIPGNR1H2NR1H3GPR3CYSLTR2 | |
| SCHEMBL11045790 | 0.85 | NR1H2 (0.39) | LIPGNR1H2NR1H3GPR3CYSLTR2 | |
| SCHEMBL10351159 | 0.84 | LIPG (0.46) | LIPGNR1H2NR1H3GPR3PTPN1 | |
| SCHEMBL8923737 | 0.84 | LIPG (0.46) | LIPGNR1H2NR1H3GPR3PTPN1 | |
| SCHEMBL9477376 | 0.84 | LIPG (0.46) | LIPGNR1H2NR1H3GPR3PTPN1 | |
| SCHEMBL7766722 | 0.84 | LIPG (0.46) | LIPGNR1H2NR1H3GPR3PTPN1 | |
| SCHEMBL11182284 | 0.84 | LIPG (0.46) | LIPGNR1H2NR1H3GPR3PTPN1 | |
| SCHEMBL8920518 | 0.84 | LIPG (0.46) | LIPGNR1H2NR1H3GPR3PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937094-A1 | METHOD FOR THE PRODUCTION OF IVERMECTIN | BAYER AG (DE) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998018806-A1 | METHOD FOR THE PRODUCTION OF IVERMECTIN | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-07 | — | — | WO | disclosed |