Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271436 | 0.94 | LIPG (0.46) | NR1H2NR1H3LIPGPPARAGPR3 | |
| SCHEMBL8519841 | 0.94 | LIPG (0.46) | NR1H2NR1H3LIPGPPARAGPR3 | |
| SCHEMBL12815176 | 0.94 | LIPG (0.46) | NR1H2NR1H3LIPGPPARAGPR3 | |
| SCHEMBL11045790 | 0.92 | NR1H2 (0.39) | NR1H2NR1H3LIPGCYP3A4CYP2D6 | |
| SCHEMBL3040415 | 0.82 | CYP2D6 (0.40) | CYP2D6TLR8PPARA | |
| SCHEMBL10437918 | 0.82 | NR1H2 (0.37) | NR1H2NR1H3LIPGCYP3A4CYP2D6 | |
| SCHEMBL2701240 | 0.82 | LIPG (0.50) | NR1H2NR1H3LIPGCYP3A4CYP2D6 | |
| SCHEMBL4450766 | 0.80 | ALOX5 (0.38) | NR1H2NR1H3LIPGCYP3A4CYP2D6 | |
| SCHEMBL11110474 | 0.80 | LIPG (0.45) | NR1H2NR1H3LIPGPPARAGPR3 | |
| SCHEMBL7798017 | 0.80 | LIPG (0.45) | NR1H2NR1H3LIPGPPARAGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036143-B1 | PHOSPHATE LUBRICANT COMPOSITIONS AND METAL FORMING USE | GREAT LAKES CHEMICAL CORP (US) | 2004-10-06 | — | — | EP | claimed |