Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095741 | 0.89 | PDE10A (0.43) | TSHRTP53MAPTHPGDALOX15 | |
| SCHEMBL8092688 | 0.83 | MAPK13 (0.43) | TSHRTP53MAPTHPGDALOX15 | |
| SCHEMBL8519868 | 0.78 | TRPV1 (0.42) | ALDH1A1LMNATRPV1F10CA12 | |
| SCHEMBL8519903 | 0.78 | MAPT (0.41) | TSHRTP53MAPTHPGDALOX15 | |
| SCHEMBL8520426 | 0.77 | ALDH1A1 (0.52) | TSHRMAPTHPGDHBBSMN1; SMN2 | |
| SCHEMBL8094384 | 0.72 | MAPK13 (0.47) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL8086490 | 0.69 | ALDH1A1 (0.42) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL8086039 | 0.68 | TSHR (0.50) | TSHRMAPTHPGDALOX15SMN1; SMN2 | |
| SCHEMBL8095193 | 0.68 | CNR1 (0.46) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL8104361 | 0.67 | ALDH1A1 (0.46) | HPGDALDH1A1LMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916905-A | ANTIARTHRITIC AGENTS; ANALGESICS; ANTIPYRETICS | G. D. SEARLE & CO. (US) | 1999-06-29 | — | — | US | disclosed |