Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14059353 | 0.86 | GAA (0.50) | ALDH1A1GAAAPAF1TDP2MAPK1 | |
| SCHEMBL24074629 | 0.83 | ALDH1A1 (0.48) | ALDH1A1GAAAPAF1TDP2MAPK1 | |
| SCHEMBL28103035 | 0.81 | HTT (0.52) | ALDH1A1GAAMAPK1HSD17B10MAPT | |
| SCHEMBL10860276 | 0.80 | ALDH1A1 (0.51) | ALDH1A1CHRM2HPGDMAPTMEN1 | |
| SCHEMBL20565356 | 0.80 | MEN1 (0.45) | MAPTABL1MEN1KMT2AHDAC3 | |
| SCHEMBL14180598 | 0.80 | APP (0.44) | ALDH1A1GAAHSD17B10HPGDMAPT | |
| SCHEMBL23350316 | 0.80 | ALDH1A1 (0.43) | ALDH1A1GAAAPAF1TDP2MAPK1 | |
| SCHEMBL23350315 | 0.80 | TLR7 (0.39) | ALDH1A1GAAHSD17B10MAPTABL1 | |
| Hydrochloric Acid SCHEMBL10440705 | 0.79 | HTT (0.54) | ALDH1A1GAAMAPK1HSD17B10CHRM2 | |
| SCHEMBL482171 | 0.79 | ABL1 (0.41) | ALDH1A1GAAAPAF1TDP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440787-B1 | COMPOUNDS OF 1,4-BIS(AMINO)BENZO(G)PHTHALAZENE | CONSEJO SUPERIOR INVESTIGACION (ES) | 1999-10-13 | — | — | EP | disclosed |