Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14059353 | 0.85 | GAA (0.50) | ABL1HDAC3HDAC2ALDH1A1GAA | |
| SCHEMBL13996560 | 0.83 | ALDH1A1 (0.41) | ALDH1A1GAAMAPK1HSD17B10MAPT | |
| SCHEMBL20565356 | 0.82 | MEN1 (0.45) | ABL1HDAC3HDAC2MGLLMAPT | |
| SCHEMBL22537442 | 0.82 | ALDH1A1 (0.43) | ALDH1A1GAAMAPK1HSD17B10APAF1 | |
| SCHEMBL15934308 | 0.81 | TUBB4A (0.55) | HDAC3HDAC2 | |
| SCHEMBL28103035 | 0.80 | HTT (0.52) | ABL1HDAC3HDAC2ALDH1A1GAA | |
| SCHEMBL24074629 | 0.79 | ALDH1A1 (0.48) | ABL1HDAC3HDAC2HDAC1ALDH1A1 | |
| SCHEMBL8519906 | 0.79 | ALDH1A1 (0.45) | ABL1HDAC3HDAC2HDAC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10440705 | 0.77 | HTT (0.54) | ABL1HDAC3HDAC2ALDH1A1GAA | |
| SCHEMBL15934214 | 0.76 | TUBB4A (0.54) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102448920-B | Antiviral compounds and uses thereof | ABBVIE (US) | 2016-04-06 | — | — | CN | disclosed |
| CN-102746239-A | Uracil or thymine derivatives for the treatment of hepatitis C | ABBOTT LAB | 2012-10-24 | — | — | CN | disclosed |
| CN-102746240-A | Anti-infective pyrimidines and uses thereof | ABBOTT LAB | 2012-10-24 | — | — | CN | disclosed |
| CN-102448920-A | Antiviral compounds and uses thereof | ABBOTT LAB | 2012-05-09 | — | — | CN | disclosed |
| EP-2411352-A2 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Abbott Laboratories (US) | 2012-02-01 | — | — | EP | disclosed |
| CN-101918369-A | Uracil or thymine derivatives for the treatment of hepatitis C | ABBOTT LAB | 2010-12-15 | — | — | CN | disclosed |
| CN-101842360-A | Anti-infective pyrimidines and uses thereof | ABBOTT LAB | 2010-09-22 | — | — | CN | disclosed |
| CN-101801935-A | Uracil or thymine derivatives for the treatment of hepatitis C | ABBOTT LAB | 2010-08-11 | — | — | CN | disclosed |