Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793579 | 0.84 | KDM4E (0.43) | KDM4ENPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL20377227 | 0.84 | FDPS (0.51) | S1PR1S1PR3PPARGGGPS1S1PR2 | |
| SCHEMBL7793618 | 0.81 | P4HTM (0.47) | KDM4ERAB9ALMNASMN1; SMN2MAPT | |
| SCHEMBL7793195 | 0.78 | KDM4E (0.44) | KDM4E | |
| SCHEMBL7794298 | 0.78 | FDPS (0.60) | KDM4ENPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL9223520 | 0.78 | KDM4E (0.44) | KDM4E | |
| SCHEMBL6243007 | 0.78 | MAPT (0.45) | KDM4EPPARGLMNASMN1; SMN2MAPT | |
| SCHEMBL7790648 | 0.74 | KMT2A (0.49) | KDM4ENPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL9220494 | 0.74 | KDM4E (0.39) | KDM4ENPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL9226173 | 0.74 | KDM4E (0.39) | KDM4ELMNAMAPTALDH1A1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866556-A | BONE DISORDERS | LEIRAS OY (FI) | 1999-02-02 | — | — | US | disclosed |