SCHEMBL8519987

SCHEMBL8519987

CC(C)=CCCC(C)(O)/C=C/O

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 7/20 0.67
KMT2A Q03164 4/20 0.38
CYP3A4 P08684 4/20 0.38
MEN1 O00255 3/20 0.38
MAPK1 P28482 1/20 0.38
CHRNA7 P36544 1/20 0.38
STAT3 P40763 1/20 0.38
HIF1A Q16665 4/20 0.36
EPAS1 Q99814 4/20 0.36
TSHR P16473 1/20 0.34
PTPN1 P18031 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 2/20 0.30
ALDH1A1 P00352 1/20 0.30
UGT1A1 P22309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28774593 1.00 ALOX15 (0.67) ALOX15KMT2ACYP3A4MEN1MAPK1
SCHEMBL8212959 0.89 ALOX15 (0.75) ALOX15KMT2ACYP3A4MEN1MAPK1
SCHEMBL15822302 0.83 ALOX15 (0.67) ALOX15KMT2ACYP3A4MEN1MAPK1
SCHEMBL15822299 0.83 ALOX15 (0.67) ALOX15KMT2ACYP3A4MEN1MAPK1
SCHEMBL13096525 0.83 ALOX15 (0.67) ALOX15KMT2ACYP3A4MEN1MAPK1
SCHEMBL29487266 0.83 ALOX15 (0.67) ALOX15KMT2ACYP3A4MEN1MAPK1
SCHEMBL8200730 0.83 ALOX15 (0.67) ALOX15KMT2ACYP3A4MEN1MAPK1
SCHEMBL30472790 0.81 ALOX15 (0.64) ALOX15KMT2ACYP3A4MEN1MAPK1
Linalool SCHEMBL988357 0.80 ALOX15 (1.00) ALOX15KMT2ACYP3A4MEN1MAPK1
Linalool SCHEMBL254425 0.80 ALOX15 (1.00) ALOX15KMT2ACYP3A4MEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10315976-B2 Organic compounds GIVAUDAN S.A. (CH) 2019-06-11 US claimed
EP-2920139-B1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2017-02-01 EP claimed
US-20160326082-A1 Organic Compounds GIVAUDAN SA (CH) 2016-11-10 US claimed
US-9469590-B2 Organic compounds GIVAUDAN S.A. (CH) 2016-10-18 US claimed
US-20150307432-A1 Improvements In or Relating to Organic Compounds GIVAUDAN S.A. (CH) 2015-10-29 US claimed
EP-0416713-B2 Process for obtaining aroma components and aromas from their precursors of a glycosidic nature, and aroma components and aromas thereby obtained DSM NV (NL) 1999-06-23 EP claimed
US-5573926-A HYDROLYSIS GIST-BROCADES, N.V. (NL) 1996-11-12 US claimed
WO-1991003174-A1 PROCESS FOR OBTAINING AROMA COMPONENTS AND AROMAS FROM THEIR PRECURSORS OF A GLYCOSIDIC NATURE, AND AROMA COMPONENTS AND AROMAS THEREBY OBTAINED GIST-BROCADES N.V. (NL) 1991-03-21 WO claimed
EP-0416713-A1 Process for obtaining aroma components and aromas from their precursors of a glycosidic nature, and aroma components and aromas thereby obtained GIST-BROCADES N.V. (NL) 1991-03-13 EP claimed
US-10315976-B2 Organic compounds GIVAUDAN S.A. (CH) 2019-06-11 US disclosed
US-20190040417-A1 BIOLOGICAL FERMENTATION USING DIHYDROXYACETONE AS A SOURCE OF CARBON KEMBIOTIX LLC (US) 2019-02-07 US disclosed
WO-2017139420-A1 BIOLOGICAL FERMENTATION USING DIHYDROXYACETONE AS A SOURCE OF CARBON KEMBIOTIX LLC (US) 2017-08-17 WO disclosed
EP-2920139-B1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2017-02-01 EP disclosed
US-20160326082-A1 Organic Compounds GIVAUDAN SA (CH) 2016-11-10 US disclosed
WO-2014198709-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2014-12-18 WO disclosed
US-5985618-A ENZYMATICALLY HYDROLYZING CIST-BROCADES, N.V. (NL) 1999-11-16 US disclosed
EP-0416713-B2 Process for obtaining aroma components and aromas from their precursors of a glycosidic nature, and aroma components and aromas thereby obtained DSM NV (NL) 1999-06-23 EP disclosed
US-5573926-A HYDROLYSIS GIST-BROCADES, N.V. (NL) 1996-11-12 US disclosed
WO-1991003174-A1 PROCESS FOR OBTAINING AROMA COMPONENTS AND AROMAS FROM THEIR PRECURSORS OF A GLYCOSIDIC NATURE, AND AROMA COMPONENTS AND AROMAS THEREBY OBTAINED GIST-BROCADES N.V. (NL) 1991-03-21 WO disclosed
EP-0416713-A1 Process for obtaining aroma components and aromas from their precursors of a glycosidic nature, and aroma components and aromas thereby obtained GIST-BROCADES N.V. (NL) 1991-03-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150307432-A1 Improvements In or Relating to Organic Compounds CYP11B2, UGT1A9, CYP11B1 ALOX15 18/4885KMT2A 3270/4885CYP3A4 38/4885
US-20160326082-A1 Organic Compounds CYP2C9, UGT1A9, CYP3A4 ALOX15 66/4885KMT2A 2668/4885CYP3A4 3/4885
US-10315976-B2 Organic compounds CYP2C9, UGT1A9, CYP3A4 ALOX15 66/4885KMT2A 2668/4885CYP3A4 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.