SCHEMBL8520120

SCHEMBL8520120

C=CCN(O)C(=O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.36
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8520279 0.98 ALDH1A1 (0.37) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL1897643 0.79
SCHEMBL9456466 0.77 ALDH1A1 (0.50) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL9067170 0.76 ALDH1A1 (0.35) ALDH1A1
SCHEMBL327516 0.76 ALDH1A1 (0.35) ALDH1A1
SCHEMBL8520277 0.76 ALDH1A1 (0.35) ALDH1A1
SCHEMBL15413189 0.73 ALDH1A1 (0.37) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL10715503 0.72 ALDH1A1 (0.39) ALDH1A1LMNA
SCHEMBL3889852 0.72
SCHEMBL676588 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE36175-E TREATING SUSCEPTIBLE PLANT WITH COMPOUND AND KETOL-ACID REDUCTOISOMERASE INHIBITOR, TREATING SECOND PLANT WITH INHIBITOR ALONE, MEASURING ACETOLACTATE AND ACETOHYDROXYBUTYRATE FORMED AMERICAN CYANAMID COMPANY (US) 1999-03-30 US claimed
US-5356789-A For plants; quantitative, colorimetric analysis AMERICAN CYANAMID COMPANY (US) 1994-10-18 US claimed
US-RE36175-E TREATING SUSCEPTIBLE PLANT WITH COMPOUND AND KETOL-ACID REDUCTOISOMERASE INHIBITOR, TREATING SECOND PLANT WITH INHIBITOR ALONE, MEASURING ACETOLACTATE AND ACETOHYDROXYBUTYRATE FORMED AMERICAN CYANAMID COMPANY (US) 1999-03-30 US disclosed
US-5356789-A For plants; quantitative, colorimetric analysis AMERICAN CYANAMID COMPANY (US) 1994-10-18 US disclosed