Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511763 | 0.73 | — | — | |
| SCHEMBL5953856 | 0.71 | CYP3A4 (0.30) | — | |
| SCHEMBL16933813 | 0.65 | IDH1 (0.44) | CALM1NR1H2NR1H3 | |
| SCHEMBL10923606 | 0.65 | CALM1 (0.41) | CALM1SIGMAR1NR1H2NR1H3 | |
| SCHEMBL27292305 | 0.65 | CALM1 (0.41) | CALM1NR1H2NR1H3 | |
| SCHEMBL8090904 | 0.65 | CALM1 (0.37) | SLC6A2CALM1 | |
| Ammonia Solution, Strong SCHEMBL7793996 | 0.64 | CALM1 (0.39) | CALM1NR1H2NR1H3 | |
| SCHEMBL253442 | 0.63 | CALM1 (0.48) | SLC6A2SLC6A4CALM1KDM1ASLC6A3 | |
| SCHEMBL27589093 | 0.63 | CALM1 (0.48) | SLC6A2SLC6A4CALM1SLC6A3SIGMAR1 | |
| SCHEMBL8088069 | 0.62 | TAAR1 (0.37) | SLC6A2SLC6A4CALM1SLC6A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922041-A1 | PROCESSES FOR PREPARING INDENO 1,2-E] 1,3,4]OXADIAZINE-DICARBOXYLATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998005656-A1 | PROCESSES FOR PREPARING INDENO[1,2-E][1,3,4]OXADIAZINE-DICARBOXYLATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-02-12 | — | — | WO | disclosed |