Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087900 | 0.81 | TP53 (0.40) | TAAR1CYP2D6MAOACALM1PTPN1 | |
| SCHEMBL8079473 | 0.79 | CALM1 (0.35) | TAAR1SIGMAR1MAOACALM1TDP1 | |
| SCHEMBL8092853 | 0.77 | CNR2 (0.37) | TAAR1SIGMAR1SLC18A2CYP2D6SLC6A2 | |
| SCHEMBL8079685 | 0.76 | SIGMAR1 (0.36) | SIGMAR1CALM1CNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8093000 | 0.75 | SIGMAR1 (0.35) | TAAR1SIGMAR1SLC18A2CYP2D6SLC6A2 | |
| SCHEMBL8090899 | 0.74 | SIGMAR1 (0.37) | TAAR1SIGMAR1SLC18A2CYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL18585839 | 0.70 | CALM1 (0.37) | TAAR1CYP2D6MAOACALM1PTPN1 | |
| SCHEMBL8090904 | 0.70 | CALM1 (0.37) | TAAR1CYP2D6SLC6A2MAOACALM1 | |
| SCHEMBL8090979 | 0.68 | CALM1 (0.42) | MAOACALM1PTPN1ALDH1A1SORT1 | |
| SCHEMBL1028381 | 0.68 | CALM1 (0.42) | TAAR1CYP2D6MAOACALM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046346-A | Production of alkali metal cyclopentadienylide and production of dihalobis (η-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0926150-A2 | Production of alkali metal cyclopentadienylide and production of dihalobis(eta-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide | Honshu Chemical Industry Co. Ltd. (JP) | 1999-06-30 | — | — | EP | disclosed |