Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 6/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 4/20 | 0.40 |
| ▸ | NOS1 | P29475 | 4/20 | 0.40 |
| ▸ | NOS2 | P35228 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8609791 | 1.00 | SLC7A5 (0.42) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL8423444 | 0.87 | NOS3 (0.40) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL8423441 | 0.87 | NOS3 (0.40) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL8425394 | 0.81 | NOS3 (0.59) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL9172559 | 0.78 | SLC7A5 (0.55) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL8609795 | 0.76 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL8423549 | 0.74 | NOS3 (0.40) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL8306982 | 0.73 | SLC7A5 (0.47) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL28318850 | 0.73 | SLC7A5 (0.47) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL8425902 | 0.73 | NOS3 (0.39) | SLC7A5PKMPTGS1ALPIXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874472-A | Aminoacid derivatives as no synthase inhibitors | GLAXO WELLCOME INC. (US) | 1999-02-23 | — | — | US | claimed |