Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.46 |
| ▸ | CCR5 | P51681 | 3/20 | 0.46 |
| ▸ | CCR8 | P51685 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2900748 | 0.85 | PLD1 (0.42) | KDM4EL3MBTL1ALOX15HTR7HTR1A | |
| Dipyridyl SCHEMBL9720335 | 0.78 | HTR7 (0.46) | CCR1CCR5CCR8KDM4EL3MBTL1 | |
| SCHEMBL5345232 | 0.77 | HTR2C (0.33) | HTR2AHTR2C | |
| SCHEMBL30983619 | 0.73 | HRH3 (0.47) | MAPK1HTR2AHTR2C | |
| SCHEMBL6017212 | 0.73 | KDM4E (0.47) | KDM4ELMNAALOX15TP53MAPK1 | |
| SCHEMBL8520211 | 0.69 | CXCR4 (0.59) | CCR1CCR5CCR8KDM4EL3MBTL1 | |
| SCHEMBL25036829 | 0.69 | CXCR4 (0.40) | HTR2AHTR2C | |
| SCHEMBL8145269 | 0.68 | SIGMAR1 (0.48) | L3MBTL1ALOX15TP53TDP1HTR7 | |
| Terpyridine SCHEMBL30610403 | 0.68 | KDM4E (0.90) | CCR1CCR5CCR8KDM4EL3MBTL1 | |
| Dipyridyl SCHEMBL29189121 | 0.68 | KDM4E (0.70) | CCR1CCR5CCR8KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874587-A | FLUORESCENCE | THE ROCKEFELLER UNIVERSITY (US) | 1999-02-23 | — | — | US | disclosed |