Biphenyl

Biphenyl

SCHEMBL8520232

O=S(=O)(O)OOS(=O)(=O)O.O=S(=O)(O)OOS(=O)(=O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.53
ALDH1A1 P00352 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
TSHR P16473 1/20 0.46
CA1 P00915 4/20 0.45
CA9 Q16790 2/20 0.45
CA12 O43570 1/20 0.44
MMP2 P08253 2/20 0.42
MMP7 P09237 1/20 0.42
MMP14 P50281 1/20 0.42
MMP3 P08254 1/20 0.42
BCL2L1 Q07817 1/20 0.42
PTPN1 P18031 1/20 0.41
MMP1 P03956 2/20 0.41
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41
MMP13 P45452 1/20 0.41
MAPT P10636 1/20 0.39
GAA P10253 1/20 0.38
MMP12 P39900 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL10337210 0.84 ALDH1A1 (0.47) CA2ALDH1A1SMN1; SMN2TSHRCA1
Biphenyl SCHEMBL7077316 0.83 ALDH1A1 (0.60) CA2ALDH1A1SMN1; SMN2TSHRCA1
Biphenyl SCHEMBL1681197 0.83 ALDH1A1 (0.60) CA2ALDH1A1SMN1; SMN2TSHRCA1
Phenol SCHEMBL28187095 0.82 CA2 (0.55) CA2ALDH1A1SMN1; SMN2TSHRCA1
Phenol SCHEMBL29145519 0.82 CA2 (0.55) CA2ALDH1A1SMN1; SMN2TSHRCA1
Biphenyl SCHEMBL27903401 0.82 ALDH1A1 (0.45) CA2ALDH1A1SMN1; SMN2TSHRCA1
Biphenyl SCHEMBL27916282 0.82 ALDH1A1 (0.45) CA2ALDH1A1SMN1; SMN2TSHRCA1
Sulfuric Acid SCHEMBL29279046 0.80 ALDH1A1 (0.56) CA2ALDH1A1SMN1; SMN2TSHRCA1
Biphenyl SCHEMBL10617373 0.80 ALDH1A1 (0.56) CA2ALDH1A1SMN1; SMN2TSHRCA1
Biphenyl SCHEMBL28140780 0.80 ALDH1A1 (0.56) CA2ALDH1A1SMN1; SMN2TSHRCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5976348-A In situ remediation of soils containing organic contaminants using the electromigration of peroxysulfate ions TENNESSEE VALLEY AUTHORITY, UNITED STATES CORPORATION (US) 1999-11-02 US disclosed