Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ADK | P55263 | 4/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623569 | 1.00 | LMNA (0.69) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL9222641 | 0.88 | LMNA (0.58) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL8520281 | 0.88 | SLC29A1 (0.56) | LMNAPMP22HBBSLC29A1PLA2G1B | |
| SCHEMBL8520282 | 0.88 | SLC29A1 (0.56) | LMNAPMP22HBBSLC29A1PLA2G1B | |
| SCHEMBL8724481 | 0.85 | LMNA (0.75) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL9222403 | 0.85 | LMNA (0.56) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL285266 | 0.85 | LMNA (0.75) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL285177 | 0.84 | LMNA (0.73) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL285088 | 0.84 | LMNA (0.73) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL285382 | 0.84 | LMNA (0.73) | LMNATSHRMAPTPMP22HBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706414-B1 | PROCESS FOR FLUOROCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-07-23 | — | — | EP | claimed |
| EP-1706414-A2 | PROCESS FOR FLUOROCYTIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2006-10-04 | — | — | EP | claimed |
| WO-2005063786-A2 | PROCESS FOR FLUOROCYTIDINE DERIVATIVES | F.HOFFMAN-LA ROCHE AG (CH) | 2005-07-14 | — | — | WO | claimed |
| EP-0698611-B1 | Process for N-acyl-5-fluorocytidine derivatives | HOFFMANN LA ROCHE (CH) | 1999-10-20 | — | — | EP | claimed |
| EP-0698611-A1 | Process for N-acyl-5-fluorocytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1996-02-28 | — | — | EP | claimed |
| US-5476932-A | Process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1995-12-19 | — | — | US | claimed |
| EP-0602478-A1 | Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-22 | — | — | EP | claimed |
| EP-1706414-B1 | PROCESS FOR FLUOROCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-07-23 | — | — | EP | disclosed |
| US-7365188-B2 | Process for producing N4-Acyl-5′-deoxy-5-fluorocytidine | ROCHE COLORADO CORPORATION (US) | 2008-04-29 | — | — | US | disclosed |
| WO-2007009303-A1 | PROCESS FOR SYNTHESIZING N4-ACYL-5'-DEOXY-5-FLUOROCYTIDINE DERIVATIVES | SHANGHAI AURISCO INTERNATIONAL TRADING CO., LTD. (CN) | 2007-01-25 | — | — | WO | disclosed |
| WO-2005063786-A3 | PROCESS FOR FLUOROCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-12-14 | — | — | WO | disclosed |
| EP-1706414-A2 | PROCESS FOR FLUOROCYTIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005063786-A2 | PROCESS FOR FLUOROCYTIDINE DERIVATIVES | F.HOFFMAN-LA ROCHE AG (CH) | 2005-07-14 | — | — | WO | disclosed |
| EP-0698611-A1 | Process for N-acyl-5-fluorocytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1996-02-28 | — | — | EP | disclosed |
| EP-0698611-A1 | Process for N-acyl-5-fluorocytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1996-02-28 | — | — | EP | disclosed |
| US-5476932-A | Process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1995-12-19 | — | — | US | disclosed |
| US-5476932-A | Process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1995-12-19 | — | — | US | disclosed |
| EP-0602478-A1 | Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-22 | — | — | EP | disclosed |
| EP-0602478-A1 | Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-22 | — | — | EP | disclosed |
| EP-0602478-A1 | Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-22 | — | — | EP | disclosed |