SCHEMBL8520401

SCHEMBL8520401

C=C(O)CN1CCNC1=O

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.42
ALDH1A1 P00352 3/20 0.42
RET P07949 1/20 0.41
KDR P35968 1/20 0.41
KMT2A Q03164 3/20 0.39
MAPT P10636 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
MEN1 O00255 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
PER2 O15055 3/20 0.36
RAB9A P51151 1/20 0.36
LMNA P02545 1/20 0.34
CRY2 Q49AN0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5590383 0.82 ALDH1A1 (0.39) POLBALDH1A1RETKDRKMT2A
SCHEMBL6429311 0.82 POLB (0.41) POLBALDH1A1RETKDRKMT2A
SCHEMBL176995 0.81 POLB (0.44) POLBALDH1A1RETKDRKMT2A
SCHEMBL17571983 0.78
SCHEMBL3452808 0.75 TSHR (0.50) POLBALDH1A1RETKDRKMT2A
SCHEMBL6877063 0.75 KMT2A (0.42) POLBALDH1A1RETKDRKMT2A
SCHEMBL7186126 0.74 KMT2A (0.37) POLBALDH1A1RETKDRKMT2A
SCHEMBL6287476 0.73 KMT2A (0.41) POLBALDH1A1RETKDRKMT2A
SCHEMBL219400 0.73
SCHEMBL634568 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0584967-A1 Polyether polyols and polyetherdiamines containing imidazolidone groups Huntsman Corporation (US) 1994-03-02 EP claimed
US-5288873-A Endcapped polyethers TEXACO CHEMICAL COMPANY (US) 1994-02-22 US claimed
JP-6206999-A None JP disclosed
EP-0732390-B1 Hydrocarbon compositions containing a polyetheramide additive HUNTSMAN CORP (US) 1999-09-22 EP disclosed
EP-0743305-A1 Polyetheramide surfactant HUNTSMAN CORPORATION (US) 1996-11-20 EP disclosed
EP-0732390-A1 Hydrocarbon compositions containing a polyetheramide additive HUNTSMAN CORPORATION (US) 1996-09-18 EP disclosed
US-5516343-A Hydrocarbon compositions containing a polyetheramide additive HUNTSMAN CORPORATION (US) 1996-05-14 US disclosed
US-5436351-A Ethylene oxide and propylene oxide polymers modified hydroxy amides and dihydroxyethylimidazolidone HUNTSMAN CORPORATION (US) 1995-07-25 US disclosed
JP-H06206999-A POLYETHERPOLYOL CONTAINING IMIDAZOLIDONE GROUP AND POLYETHERDIAMINE TEXACO CHEM CO 1994-07-26 JP disclosed
EP-0584967-A1 Polyether polyols and polyetherdiamines containing imidazolidone groups Huntsman Corporation (US) 1994-03-02 EP disclosed
US-5288873-A Endcapped polyethers TEXACO CHEMICAL COMPANY (US) 1994-02-22 US disclosed
US-5238971-A Flexible foams TEXACO CHEMICAL COMPANY (US) 1993-08-24 US disclosed
US-4632957-A ADHESION PROMOTER PPG INDUSTRIES, INC. (US) 1986-12-30 US disclosed
EP-0180736-A1 Ethylenically unsaturated imidazolidones containing alkylene urea groups or alkylene urethane groups PPG INDUSTRIES, INC. (US) 1986-05-14 EP disclosed