Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.56 |
| ▸ | HPGD | P15428 | 7/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.56 |
| ▸ | CA12 | O43570 | 4/20 | 0.56 |
| ▸ | CA9 | Q16790 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4187358 | 0.98 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| SCHEMBL6245154 | 0.97 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| Glycine SCHEMBL4176892 | 0.87 | ALDH1A1 (0.75) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| Glycine SCHEMBL335759 | 0.85 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| Glycine SCHEMBL4627607 | 0.84 | ALDH1A1 (0.75) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| Hydrochloric Acid SCHEMBL4170610 | 0.83 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| SCHEMBL4187096 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| SCHEMBL6424932 | 0.81 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| Hydrochloric Acid SCHEMBL8520013 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| D-Alanine SCHEMBL4187196 | 0.79 | ALDH1A1 (0.75) | ALDH1A1KDM4EHPGDHSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946746-A1 | METHOD AND COMPONENTS FOR THE DETECTION OF YEASTS AND/OR MOLDS IN A SAMPLE | IDEXX LABORATORIES, INC. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027223-A1 | METHOD AND COMPONENTS FOR THE DETECTION OF YEASTS AND/OR MOLDS IN A SAMPLE | IDEXX LABORATORIES, INCORPORATED (US) | 1998-06-25 | — | — | WO | disclosed |