Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5278858 | 0.98 | ALDH1A1 (0.44) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL475866 | 0.96 | ALDH1A1 (0.42) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL26390223 | 0.86 | CHRNB2 (0.37) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL5275929 | 0.82 | ALDH1A1 (0.44) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Iodide SCHEMBL1396478 | 0.82 | ALDH1A1 (0.48) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Iodide SCHEMBL7952992 | 0.81 | CHRNA7 (0.42) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL475899 | 0.81 | ALDH1A1 (0.42) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Iodide SCHEMBL30051078 | 0.80 | CHRNB2 (0.38) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Iodide SCHEMBL30050911 | 0.80 | CHRNB2 (0.38) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL1476194 | 0.80 | CHRNA7 (0.51) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240138720-A1 | ANALYTE SENSOR | DEXCOM, INC. (US) | 2024-05-02 | — | — | US | disclosed |
| EP-4324921-A2 | BIOINTERFACE LAYER FOR ANALYTE SENSORS | Dexcom, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |
| US-20240041356-A1 | POLYMER MEMBRANES FOR CONTINUOUS ANALYTE SENSORS | DEXCOM, INC. (US) | 2024-02-08 | — | — | US | disclosed |
| EP-4292528-A1 | MEMBRANE LAYERS FOR ANALYTE SENSORS | Dexcom, Inc. (US) | 2023-12-20 | — | — | EP | disclosed |
| EP-3397398-B1 | BIOINTERFACE LAYER FOR ANALYTE SENSORS | DEXCOM INC (US) | 2023-11-08 | — | — | EP | disclosed |
| EP-4253536-A2 | DIFFUSION RESISTANCE LAYER FOR ANALYTE SENSORS | DexCom, Inc. (US) | 2023-10-04 | — | — | EP | disclosed |
| EP-3397163-B1 | DIFFUSION RESISTANCE LAYER FOR ANALYTE SENSORS | DEXCOM INC (US) | 2023-09-13 | — | — | EP | disclosed |
| EP-3397162-B1 | MEMBRANE LAYERS FOR ANALYTE SENSORS | DEXCOM INC (US) | 2023-09-06 | — | — | EP | disclosed |
| EP-4218566-A1 | ENZYME IMMOBILIZED ADHESIVE LAYER FOR ANALYTE SENSORS | Dexcom, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-4218570-A2 | POLYMER MEMBRANES FOR CONTINUOUS ANALYTE SENSORS | DexCom, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2017117565-A1 | MEMBRANE LAYERS FOR ANALYTE SENSORS | DEXCOM, INC. (US) | 2017-07-06 | — | — | WO | disclosed |
| WO-2017117468-A1 | ENZYME IMMOBILIZED ADHESIVE LAYER FOR ANALYTE SENSORS | DEXCOM, INC. (US) | 2017-07-06 | — | — | WO | disclosed |
| WO-2017117469-A1 | DIFFUSION RESISTANCE LAYER FOR ANALYTE SENSORS | DEXCOM, INC. (US) | 2017-07-06 | — | — | WO | disclosed |
| WO-2017117472-A1 | BIOINTERFACE LAYER FOR ANALYTE SENSORS | DEXCOM, INC. (US) | 2017-07-06 | — | — | WO | disclosed |
| US-9549692-B2 | Polymer membranes for continuous analyte sensors | DEXCOM, INC. (US) | 2017-01-24 | — | — | US | disclosed |
| EP-2747650-A1 | POLYMER MEMBRANES FOR CONTINUOUS ANALYTE SENSORS | Dexcom, Inc. (US) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013032940-A1 | POLYMER MEMBRANES FOR CONTINUOUS ANALYTE SENSORS | DEXCOM, INC. (US) | 2013-03-07 | — | — | WO | disclosed |
| US-20130053665-A1 | POLYMER MEMBRANES FOR CONTINUOUS ANALYTE SENSORS | DEXCOM, INC. (US) | 2013-02-28 | — | — | US | disclosed |
| US-20130053666-A1 | POLYMER MEMBRANES FOR CONTINUOUS ANALYTE SENSORS | DEXCOM, INC. (US) | 2013-02-28 | — | — | US | disclosed |
| US-5964794-A | Implantable stimulation electrode | BIOTRONIK MESS- UND THERAPIEGERAETE GMBH & CO. INGENIEURBUERO BERLIN (DE) | 1999-10-12 | — | — | US | disclosed |