SCHEMBL8520644

SCHEMBL8520644

C#CO[Si](C)(C)C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1699087 0.71
SCHEMBL3381957 0.69
SCHEMBL4771523 0.67
SCHEMBL1327834 0.67
SCHEMBL135371 0.65 POLB (0.32)
SCHEMBL6630878 0.65
SCHEMBL336315 0.64
SCHEMBL1057560 0.64
SCHEMBL9084961 0.64
SCHEMBL2644262 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0742223-B1 A method of preparing a derivative of optically active azetidin-2-one TAKASAGO PERFUMERY CO LTD (JP) 1999-11-17 EP claimed
EP-0336143-B1 A NEW PROCESS FOR CARBAPENEM INTERMEDIATES SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1993-06-09 EP claimed
EP-4665717-A2 USES OF CERTAIN 1,4-OXAZEPANE-2-CARBOXAMIDES AS DPP1 INHIBITORS Insmed Incorporated (US) 2025-12-24 EP disclosed
WO-2024173556-A2 USES OF CERTAIN 1,4-OXAZEPANE-2-CARBOXAMIDES AS DPP1 INHIBITORS INSMED INCORPORATED (US) 2024-08-22 WO disclosed
EP-2960342-A1 INFLAMMATORY BOWEL DISEASE PROGNOSTICS Nestec S.A. (CH) 2015-12-30 EP disclosed