SCHEMBL8520668

SCHEMBL8520668

CCOP(=O)(O)ONC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
TSHR P16473 2/20 0.37
PLA2G2A P14555 2/20 0.36
TP53 P04637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
PGGT1B P53609 1/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
CYP2D6 P10635 1/20 0.32
CYP3A4 P08684 1/20 0.32
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28963629 0.81 PPARD (0.33) PPARDCA12CA1CA2CA9
SCHEMBL11899217 0.81 TSHR (0.50) PPARDCA12CA1CA2CA9
SCHEMBL11322516 0.78
Diethyl Hydrogen Phosphate SCHEMBL27873286 0.78 TSHR (0.43) PPARDCA12CA1CA2CA9
SCHEMBL27524340 0.78 CA12 (0.36) PPARDCA12CA1CA2CA9
SCHEMBL317090 0.77 TSHR (0.33) PPARDCA12CA1CA2CA9
Diethyl Hydrogen Phosphate SCHEMBL31065172 0.77 TSHR (0.48) PPARDCA12CA1CA2CA9
SCHEMBL3457673 0.76
Diethyl Hydrogen Phosphate SCHEMBL376684 0.75 TSHR (0.46) PPARDCA12CA1CA2CA9
SCHEMBL31419774 0.74 BTN3A1 (0.39) TDP1FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6005004-A POLYLYSINE, POLYARGININE AND POLYORNITHINE BIMOLECULAR COMPLEXES MOLECULAR / STRUCTURAL BIOTECHNOLOGIES, INC. (US) 1999-12-21 US disclosed