SCHEMBL317090

SCHEMBL317090

C=CC(=O)NOP(=O)(O)OCC

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.33
PPARD Q03181 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
MAPK1 P28482 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
TP53 P04637 1/20 0.30
FNTA P49354 1/20 0.30
FNTB P49356 1/20 0.30
PGGT1B P53609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28638981 0.86 ZDHHC20 (0.35) TSHRALDH1A1TDP1MAPK1ZDHHC20
SCHEMBL9815384 0.81 TSHR (0.41) TSHRALDH1A1TDP1MAPK1
SCHEMBL28150271 0.80 CHRM5 (0.37) TSHRMAPK1
SCHEMBL28432765 0.78 TSHR (0.35) TSHRALDH1A1TDP1MAPK1ZDHHC20
SCHEMBL8520668 0.77 PPARD (0.38) TSHRPPARDALDH1A1TDP1CA12
SCHEMBL27872966 0.77 TSHR (0.36) TSHRCA12CA1CA2CA9
SCHEMBL16402987 0.76 TDP1 (0.35) TSHRALDH1A1TDP1MAPK1FNTA
SCHEMBL28963629 0.75 PPARD (0.33) TSHRPPARDALDH1A1TDP1CA12
Diethyl Hydrogen Phosphate SCHEMBL27555998 0.75 LMNA (0.43) TSHRPPARDALDH1A1TDP1CA12
SCHEMBL27813651 0.75 TSHR (0.37) TSHRALDH1A1TDP1MAPK1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1508042-A4 BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS BIO RAD LABORATORIES (US) 2008-04-02 EP claimed
EP-1508042-A2 BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS Ciphergen Biosystems, Inc. (US) 2005-02-23 EP claimed
US-20030218130-A1 Biochips with surfaces coated with polysaccharide-based hydrogels CIPHERGEN BIOSYSTEMS, INC. 2003-11-27 US claimed
WO-2003093785-A2 BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS CIPHERGEN BIOSYSTEMS, INC. (US) 2003-11-13 WO claimed
CN-119731560-A Contact lens having hydrogel coating thereon 爱尔康公司 2025-03-28 CN disclosed
EP-2909606-B1 DEVICE AND METHODS OF USING DEVICE FOR DETECTION OF AMINOACIDOPATHIES UNIV MARYLAND (US) 2023-12-06 EP disclosed
CN-115772245-A High-robustness phosphate water reducing agent special for self-compacting concrete and preparation method thereof 深中通道管理中心 2023-03-10 CN disclosed
CN-112745464-A Phosphate-containing high-adaptability early-strength polycarboxylate superplasticizer and preparation method and application thereof 广州市建筑科学研究院有限公司 2021-05-04 CN disclosed
EP-3540429-B1 DEVICE AND METHODS OF USING DEVICE FOR DETECTION OF HYPERAMMONEMIA UNIV MARYLAND (US) 2020-11-11 EP disclosed
US-10620187-B2 Device and methods of using device for detection of hyperammonemia UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2020-04-14 US disclosed
US-10591495-B2 Device and methods of using device for detection of hyperammonemia UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2020-03-17 US disclosed
EP-3540429-A1 DEVICE AND METHODS OF USING DEVICE FOR DETECTION OF HYPERAMMONEMIA University of Maryland, College Park (US) 2019-09-18 EP disclosed
WO-2015031911-A1 DEVICE AND METHODS OF USING DEVICE FOR DETECTION OF HYPERAMMONEMIA UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2015-03-05 WO disclosed
WO-2014062985-A1 DEVICE AND METHODS OF USING DEVICE FOR DETECTION OF AMINOACIDOPATHIES UNIVERSITY OF MARYLAND, OFFICE OF TECHNOLOGY COMMERCIALIZATION (US) 2014-04-24 WO disclosed
US-8092993-B2 Hydrogel thin film for use as a biosensor NELLCOR PURITAN BENNETT LLC (US) 2012-01-10 US disclosed
US-20090170124-A1 HYDROGEL THIN FILM FOR USE AS A BIOSENSOR NELLCOR PURITAN BENNETT LLC (US) 2009-07-02 US disclosed
EP-1508042-A4 BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS BIO RAD LABORATORIES (US) 2008-04-02 EP disclosed
EP-1508042-A2 BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS Ciphergen Biosystems, Inc. (US) 2005-02-23 EP disclosed
US-20030218130-A1 Biochips with surfaces coated with polysaccharide-based hydrogels CIPHERGEN BIOSYSTEMS, INC. 2003-11-27 US disclosed
WO-2003093785-A2 BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS CIPHERGEN BIOSYSTEMS, INC. (US) 2003-11-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10591495-B2 Device and methods of using device for detection of hyperammonemia ASS1, ALPL, SLCO2B1 TSHR 2398/4885PPARD 3367/4885ALDH1A1 1469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.