Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.72 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.51 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22247832 | 0.96 | CHRM2 (0.70) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL10363909 | 0.94 | MAOA (0.76) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL2315417 | 0.86 | MEN1 (0.73) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL893154 | 0.86 | MAOA (0.86) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL4932707 | 0.86 | MAOA (0.95) | MAOACHRM2MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL4370015 | 0.84 | MEN1 (0.70) | MAOACHRM2MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL3524869 | 0.84 | MAOA (0.82) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL4642587 | 0.84 | MAOA (1.00) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL8851048 | 0.84 | MAOA (1.00) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL16260102 | 0.84 | MAOA (1.00) | MAOACHRM2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115323-B1 | PROCESS FOR PRODUCING HETEROCYCLIC COMPOUND HAVING NITROMETHYLENE GROUP AS THE SIDE CHAIN GROUP | UBE INDUSTRIES, LTD. (JP) | 1990-08-29 | — | — | EP | claimed |
| US-4665172-A | Process for producing heterocyclic compound having nitromethylene group as the side chain group | UBE INDUSTRIES, LTD. (JP) | 1987-05-12 | — | — | US | claimed |
| US-4625025-A | Process for producing a 2H-1,3-thiazolidine, 2H-tetrahydro-1,3-thiazine, or 2H-hexahydro-1,3-thiazepine derivative substituted at the 2 position by a nitromethylene group derivative | UBE INDUSTRIES, LTD. (JP) | 1986-11-25 | — | — | US | claimed |
| EP-0135803-A2 | Process for producing heterocyclic compounds having nitromethylene group as the side chain group | UBE INDUSTRIES, LTD. (JP) | 1985-04-03 | — | — | EP | claimed |
| EP-0115323-A2 | Process for producing heterocyclic compound having nitromethylene group as the side chain group | UBE INDUSTRIES, LTD. (JP) | 1984-08-08 | — | — | EP | claimed |
| EP-0948527-A1 | CYCLOSPORIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998028329-A1 | CYCLOSPORIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1998-07-02 | — | — | WO | disclosed |
| EP-0115323-B1 | PROCESS FOR PRODUCING HETEROCYCLIC COMPOUND HAVING NITROMETHYLENE GROUP AS THE SIDE CHAIN GROUP | UBE INDUSTRIES, LTD. (JP) | 1990-08-29 | — | — | EP | disclosed |
| US-4665172-A | Process for producing heterocyclic compound having nitromethylene group as the side chain group | UBE INDUSTRIES, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| US-4625025-A | Process for producing a 2H-1,3-thiazolidine, 2H-tetrahydro-1,3-thiazine, or 2H-hexahydro-1,3-thiazepine derivative substituted at the 2 position by a nitromethylene group derivative | UBE INDUSTRIES, LTD. (JP) | 1986-11-25 | — | — | US | disclosed |
| EP-0135803-A2 | Process for producing heterocyclic compounds having nitromethylene group as the side chain group | UBE INDUSTRIES, LTD. (JP) | 1985-04-03 | — | — | EP | disclosed |
| EP-0115323-A2 | Process for producing heterocyclic compound having nitromethylene group as the side chain group | UBE INDUSTRIES, LTD. (JP) | 1984-08-08 | — | — | EP | disclosed |