Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572004 | 0.82 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL27624951 | 0.82 | IKBKB (0.54) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL4903727 | 0.82 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL7564771 | 0.82 | RAD52 (0.59) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL8519391 | 0.81 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL27996192 | 0.76 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL902623 | 0.76 | ALDH1A1 (0.66) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL27449616 | 0.74 | TLR8 (0.49) | ALDH1A1KDM4ERAD52KMT2AMEN1 | |
| SCHEMBL18422726 | 0.74 | ALDH1A1 (0.74) | ALDH1A1RAB9AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL7596404 | 0.74 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |