Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 11/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421878 | 0.81 | CHRNA7 (0.36) | TACR1SLC18A3GBA1CHRNA7 | |
| SCHEMBL8420280 | 0.74 | HRH3 (0.33) | CYP2D6 | |
| SCHEMBL8417764 | 0.71 | HPGD (0.34) | ALDH1A1 | |
| SCHEMBL8419827 | 0.70 | CYP2D6 (0.31) | CYP2D6 | |
| SCHEMBL8419750 | 0.70 | SMN1; SMN2 (0.34) | ALDH1A1 | |
| SCHEMBL8421972 | 0.69 | ACACB (0.38) | — | |
| SCHEMBL8712010 | 0.69 | CYP1A1 (0.38) | SLC18A3 | |
| Hydrochloric Acid SCHEMBL8421977 | 0.68 | FDFT1 (0.33) | ALDH1A1 | |
| SCHEMBL31071608 | 0.68 | FFAR1 (0.41) | FFAR1 | |
| SCHEMBL8419673 | 0.67 | FDFT1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |