Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707234 | 0.87 | HRH3 (0.37) | GRM5HRH3KDM4E | |
| SCHEMBL8920052 | 0.76 | KMT2A (0.53) | CYP1A2SLC18A3KDM4EMEN1NPC1 | |
| SCHEMBL8574139 | 0.75 | CHRNA7 (0.50) | CYP1A2GRM5 | |
| SCHEMBL8921220 | 0.75 | MCHR1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL8578709 | 0.74 | CHRNA7 (0.49) | CYP1A2GRM5 | |
| SCHEMBL8921686 | 0.73 | MEN1 (0.38) | CYP1A2SLC18A3KDM4EMEN1NPC1 | |
| SCHEMBL8421878 | 0.72 | CHRNA7 (0.36) | SLC18A3 | |
| SCHEMBL8573706 | 0.70 | TTR (0.41) | CYP1A2GRM5HRH3KDM4ENPC1 | |
| SCHEMBL3259554 | 0.69 | ALPL (0.34) | HRH3SLC18A3KMT2A | |
| SCHEMBL8520797 | 0.69 | FFAR1 (0.38) | SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770608-A | ANTICHOLESTEROL AGENTS FOR TREATING CARDIOVASCULAR DISORDERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1998-06-23 | — | — | US | disclosed |