Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417915 | 0.82 | ACACB (0.37) | HRH3USP30CYP2D6OPRM1 | |
| SCHEMBL8417740 | 0.75 | HRH3 (0.34) | HRH3FFAR4CHEK2HTR1ACYP2D6 | |
| SCHEMBL8421884 | 0.74 | KDM4E (0.34) | SLC6A4 | |
| SCHEMBL8419842 | 0.73 | HTR1A (0.34) | HTR1A | |
| SCHEMBL8420485 | 0.73 | FDFT1 (0.36) | — | |
| SCHEMBL8921318 | 0.72 | ALDH1A1 (0.45) | HRH3CYP2D6 | |
| SCHEMBL8422069 | 0.72 | CTSK (0.42) | HTR1A | |
| SCHEMBL8421763 | 0.72 | EGFR (0.34) | HRH3 | |
| SCHEMBL8969567 | 0.71 | FDFT1 (0.51) | — | |
| Hydrochloric Acid SCHEMBL8919722 | 0.71 | ALDH1A1 (0.44) | HRH3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |