Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284141 | 0.88 | APLNR (0.55) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL4150198 | 0.83 | APLNR (0.47) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL11525177 | 0.83 | MEN1 (0.56) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL289320 | 0.81 | APLNR (0.46) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL24514107 | 0.81 | APLNR (0.50) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL8568535 | 0.80 | APLNR (0.42) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL17960 | 0.80 | — | — | |
| SCHEMBL5073789 | 0.79 | APLNR (0.44) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL18329993 | 0.79 | APLNR (0.44) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL8134537 | 0.79 | APLNR (0.44) | APLNRGAAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934081-A2 | ANTINEOPLASTIC CONJUGATES OF TRANSFERRIN, ALBUMIN AND POLYETHYLENE GLYCOL | Kratz, Felix (DE) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998010794-A2 | ANTINEOPLASTIC CONJUGATES OF TRANSFERRIN, ALBUMIN AND POLYETHYLENE GLYCOL | KRATZ FELIX (DE) | 1998-03-19 | — | — | WO | disclosed |