Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525177 | 0.94 | MEN1 (0.56) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL24514107 | 0.92 | APLNR (0.50) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL1717954 | 0.89 | APLNR (0.48) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL19273270 | 0.89 | APLNR (0.48) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL1935332 | 0.89 | APLNR (0.48) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL8520807 | 0.88 | APLNR (0.47) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL4150198 | 0.88 | APLNR (0.47) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL3709746 | 0.87 | APLNR (0.47) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL289320 | 0.86 | APLNR (0.46) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL25198094 | 0.85 | APLNR (0.46) | APLNRGAAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 387 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11398630-B2 | Method of generating energy from a hydrazide containing anode fuel, and fuel cell | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2022-07-26 | — | — | US | claimed |
| CN-110066286-B | Phenylpyrazoline compound with biological activity and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-06-16 | — | — | CN | claimed |
| US-12638441-B1 | Linker compounds | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2026-05-26 | — | — | US | disclosed |
| EP-4735430-A1 | MALT1 INHIBITORS | Janssen Pharmaceutica NV (BE) | 2026-05-06 | — | — | EP | disclosed |
| US-20260108619-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2026-04-23 | — | — | US | disclosed |
| US-20260091081-A1 | A FORMULATION OF A CONJUGATE OF A TUBULYSIN ANALOG TO A CELL-BINDING MOLECULE | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2026-04-02 | — | — | US | disclosed |
| US-12576124-B2 | Formulation of a conjugate of a tubulysin analog to a cell-binding molecule | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2026-03-17 | — | — | US | disclosed |
| US-12508321-B2 | Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2025-12-30 | — | — | US | disclosed |
| US-12496351-B2 | Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2025-12-16 | — | — | US | disclosed |
| EP-4653419-A1 | LINKER FOR ANTIBODY-DRUG CONJUGATES, AND ANTIBODY-DRUG CONJUGATE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2025-11-26 | — | — | EP | disclosed |
| US-12472265-B2 | Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2025-11-18 | — | — | US | disclosed |
| US-5912388-A | IN THE PRESENCE OF A BASE, A CATALYTIC AMOUNT OF A COPPER SALT AND A SUITABLE LIGNAD UNDER ANHYDROUS CONDITIONS. | ZENECA LIMITED (GB) | 1999-06-15 | — | — | US | disclosed |
| WO-1998051654-A1 | CATALYTIC OXIDATIVE PROCESS FOR PREPARING CARBOXYLIC ACIDS FROM ALCOHOLS OR ALDEHYDES | ZENECA LIMITED (GB) | 1998-11-19 | — | — | WO | disclosed |
| US-5817602-A | Herbicidal thiadiazabicyclodecanes | NOVARTIS CORPORATION (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0840717-A1 | PREPARATION OF ALDEHYDES OR KETONES FROM ALCOHOLS | ZENECA LIMITED (GB) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997003033-A1 | PREPARATION OF ALDEHYDES OR KETONES FROM ALCOHOLS | ZENECA LIMITED (GB) | 1997-01-30 | — | — | WO | disclosed |
| US-5494889-A | THIADIAZABICYCLOOCTANE AND THIADIAZABICYCLOOCTENE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1996-02-27 | — | — | US | disclosed |
| US-5416065-A | Herbicidal thiadiazabicyclooctanes | CIBA-GEIGY CORPORATION (US) | 1995-05-16 | — | — | US | disclosed |
| WO-1992021684-A1 | NEW HERBICIDES | CIBA-GEIGY AG (CH) | 1992-12-10 | — | — | WO | disclosed |
| EP-0024372-A1 | Derivatives of clavulanic acid, their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1981-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12508321-B2 | Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers | CD4, CD2, B2M | APLNR 2933/4885GAA 1994/4885MEN1 780/4885 |
| US-12576124-B2 | Formulation of a conjugate of a tubulysin analog to a cell-binding molecule | CD4, TAP1, MCTS1 | APLNR 446/4885GAA 3324/4885MEN1 104/4885 |
| US-12496351-B2 | Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers | CD2BP2, DCLRE1A, EPCAM | APLNR 151/4885GAA 3026/4885MEN1 2291/4885 |
| US-12638441-B1 | Linker compounds | CD79B, FCGR2A, FCGRT | APLNR 498/4885GAA 3632/4885MEN1 1507/4885 |
| US-20260091081-A1 | A FORMULATION OF A CONJUGATE OF A TUBULYSIN ANALOG TO A CELL-BINDING MOLECULE | CD4, MALT1, LY6K | APLNR 256/4885GAA 3674/4885MEN1 385/4885 |
| US-12472265-B2 | Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers | CD2BP2, DCLRE1A, EPCAM | APLNR 151/4885GAA 3026/4885MEN1 2291/4885 |
| US-20260108619-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | DCLRE1A, CCR3, CCR8 | APLNR 132/4885GAA 3588/4885MEN1 2393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.